Twitter Reacts to Iowa State Upsetting Oklahoma

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Heisman Trophy odds and National Championship aspirations can burn on a fall Saturday afternoon if you’re not careful, just ask Baker Mayfield and the Oklahoma Sooners.

This is the 7th straight season Oklahoma has lost a game in which it was a double-digit favorite, and today’s upset loss to Iowa State, who had a quarterback quit just days before, was shocking.

Twitter reacts to everything, and this upset loss was no different:

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