A 16 seed has never upset a No. 1 seed in the NCAA tournament.
Everything else is always up for grabs every March Madness. Iowa State found out the hard way, destroying thousands of brackets after laying a brutal egg against UAB.
UAB, the 14th seed in the South, stunned 3rd seeded Iowa State, 60-59, sending the Big 12 tournament champs home early.
The game winner –- a Wiliam Lee jumper from the foul line with :23 left — could have been Fred Hoiberg’s final game with Iowa State.
h.t MS1